| 中文名称 |
AF/LE Purified Anti-Human CD105 Antibody[SN6] |
| 英文名称 |
AF/LE Purified Anti-Human CD105 Antibody[SN6] |
| 反应性 |
Human |
| 克隆编号 |
SN6 |
| 亚型 |
Mouse IgG1,κ |
| 经过验证的样品 |
Verified Samples in FCM: U937 |
| 稀释 |
FCM 2 μg/mL(1×105-5×105cells) |
| Swissprot |
P17813 |
| 纯化方法 |
>98%, Protein A/G purified |
| 研究领域 |
Immunology;Stem Cells;Cancer;Cardiovascular |
| 共轭 |
None (AF/LE) |
| 存储缓冲区 |
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| 免疫原 |
Recombinant Human CD105 protein |
| 应用范围 |
FCM |
| 宿主 |
Mouse |
| 克隆性 |
Monoclonal |
| 储存条件 |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| 有效期 |
12个月 |
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins (1-3). Endoglin and Betaglycan/T beta RIII are type III receptors for TGF beta superfamily ligands, sharing 71% aa identity in the transmembrane (TM) and cytoplasmic domains. Endoglin is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta, with lower amounts on hematopoietic, mesenchymal and neural crest stem cells, activated monocytes, and lymphoid and myeloid leukemic cells.
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