| 中文名称 |
Purified Anti-Human CD32 Antibody[IV-3] |
| 英文名称 |
Purified Anti-Human CD32 Antibody[IV-3] |
| 反应性 |
Human |
| 克隆编号 |
IV-3 |
| 亚型 |
Mouse IgG2b, κ |
| 经过验证的样品 |
Verified Samples in FCM: Human peripheral blood granulocyte |
| 稀释 |
FCM 2 μg/mL(1×105-5×105cells) |
| Swissprot |
P31994 |
| 纯化方法 |
>98%, Protein A/G purified |
| 研究领域 |
Immunology;Innate Immunity |
| 共轭 |
Unconjugated |
| 存储缓冲区 |
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| 免疫原 |
Recombinant Human CD32 protein |
| 应用范围 |
FCM;Block |
| 宿主 |
Mouse |
| 克隆性 |
Monoclonal |
| 储存条件 |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| 有效期 |
12个月 |
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
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