| 中文名称 |
AF/LE Purified Anti-Human CD16 Antibody[3G8] |
| 英文名称 |
AF/LE Purified Anti-Human CD16 Antibody[3G8] |
| 反应性 |
Human |
| 克隆编号 |
3G8 |
| 亚型 |
Mouse IgG1, κ |
| 经过验证的样品 |
Verified Samples in FCM: Human peripheral blood lymphocytes |
| 稀释 |
FCM 2 μg/mL(1×105-5×105cells) |
| Swissprot |
P08637,O75015 |
| 纯化方法 |
>98%, Protein A/G purified |
| 研究领域 |
Immunology;Stem Cells;Immunology |
| 共轭 |
None (AF/LE) |
| 存储缓冲区 |
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| 免疫原 |
Recombinant Human CD16 protein |
| 应用范围 |
FCM;Block |
| 宿主 |
Mouse |
| 克隆性 |
Monoclonal |
| 储存条件 |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| 有效期 |
12个月 |
CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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业务员小罗
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