| 中文名称 |
AF/LE Purified Anti-Human CD20 Antibody[2H7] |
| 英文名称 |
AF/LE Purified Anti-Human CD20 Antibody[2H7] |
| 反应性 |
Human |
| 克隆编号 |
2H7 |
| 亚型 |
Mouse IgG2b, κ |
| 经过验证的样品 |
Verified Samples in FCM: Human peripheral blood lymphocytes |
| 稀释 |
FCM 2 μg/mL(1×105-5×105cells) |
| Swissprot |
P11836 |
| 纯化方法 |
>98%, Protein A/G purified |
| 研究领域 |
Costimulatory Molecules;Immunology |
| 共轭 |
None (AF/LE) |
| 存储缓冲区 |
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| 免疫原 |
Recombinant Human CD20 protein |
| 应用范围 |
FCM |
| 宿主 |
Mouse |
| 克隆性 |
Monoclonal |
| 储存条件 |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| 有效期 |
12个月 |
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
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