| 中文名称 |
AF/LE Purified Anti-Human CD14 Antibody[M5E2] |
| 英文名称 |
AF/LE Purified Anti-Human CD14 Antibody[M5E2] |
| 反应性 |
Human |
| 克隆编号 |
M5E2 |
| 亚型 |
Mouse IgG2a, κ |
| 经过验证的样品 |
Verified Samples in FCM: Human peripheral blood monocytes |
| 稀释 |
FCM 2 μg/mL(1×105-5×105cells) |
| Swissprot |
P08571 |
| 纯化方法 |
>98%, Protein A/G purified |
| 研究领域 |
Immunology;Stem Cells;Kits;Lysates;Other |
| 共轭 |
None (AF/LE) |
| 存储缓冲区 |
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| 免疫原 |
Recombinant Human CD14 protein |
| 应用范围 |
FCM |
| 宿主 |
Mouse |
| 克隆性 |
Monoclonal |
| 储存条件 |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| 有效期 |
12个月 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.
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