| 中文名称 |
AF/LE Purified Anti-Human CD197 Antibody[G043H7] |
| 英文名称 |
AF/LE Purified Anti-Human CD197 Antibody[G043H7] |
| 反应性 |
Human |
| 克隆编号 |
G043H7 |
| 亚型 |
Mouse IgG2a, κ |
| 经过验证的样品 |
Verified Samples in FCM: Human peripheral blood lymphocytes |
| 稀释 |
FCM 2 μg/mL(1×105-5×105cells) |
| Swissprot |
P32248 |
| 纯化方法 |
>98%, Protein A/G purified |
| 研究领域 |
Immunology;Signal Transduction |
| 共轭 |
None (AF/LE) |
| 存储缓冲区 |
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| 免疫原 |
Recombinant Human CD197 protein |
| 应用范围 |
FCM |
| 宿主 |
Mouse |
| 克隆性 |
Monoclonal |
| 储存条件 |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| 有效期 |
12个月 |
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
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