| 中文名称 |
Purified Anti-Human CD35 Antibody[E11] |
| 英文名称 |
Purified Anti-Human CD35 Antibody[E11] |
| 反应性 |
Human |
| 克隆编号 |
E11 |
| 亚型 |
Mouse IgG1, κ |
| Swissprot |
P17927 |
| 研究领域 |
Cell Biology;Complement;Immunology;Neuroinflammation;Neuroscience |
| 共轭 |
Unconjugated |
| 存储缓冲区 |
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| 应用范围 |
FCM |
| 宿主 |
Mouse |
| 克隆性 |
Monoclonal |
| 储存条件 |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| 有效期 |
12个月 |
CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.
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