工作时间:08:30-17:30
NDE1 MS Standard C13 and N15-labeled recombinant protein (NP_001137451)
OR-PH327919
OriGene
¥19520.00
规格 市场价 会员价
¥19520.00
中文名称 NDE1 MS Standard C13 and N15-labeled recombinant protein (NP_001137451)
英文名称 NDE1 MS Standard C13 and N15-labeled recombinant protein (NP_001137451)
观察到的分子量 37.7 kDa
缓冲区 25 mM Tris-HCl, 100 mM glycine, pH 7.3
序列 [RC227919]
宿主 HEK293
来源 Human
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

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