| 中文名称 |
API5 MS Standard C13 and N15-labeled recombinant protein (NP_001136403) |
| 英文名称 |
API5 MS Standard C13 and N15-labeled recombinant protein (NP_001136403) |
| 观察到的分子量 |
50.6 kDa |
| 缓冲区 |
25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| 序列 |
[RC227863] |
| 宿主 |
HEK293 |
| 来源 |
Human |
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
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