| 中文名称 |
A2ML1 MS Standard C13 and N15-labeled recombinant protein (NP_653271) |
| 英文名称 |
A2ML1 MS Standard C13 and N15-labeled recombinant protein (NP_653271) |
| 观察到的分子量 |
161 kDa |
| 缓冲区 |
25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| 序列 |
[RC219615] |
| 宿主 |
HEK293 |
| 来源 |
Human |
This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
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