Anti-APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI5C5 (formerly 5C5), HRP conjugated

货号： OR-TA500972BM

品牌： OriGene

原商品链接： https://www.origene.com.cn/search?model=&fromPage=ivd&q=TA500972BM

价格：会员价请登录

￥3990.00

纯度/规格：

100 ul

包装：

支

数量：

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规格	市场价	会员价
支	¥3990.00

产品信息

中文名称	Anti-APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI5C5 (formerly 5C5), HRP conjugated
英文名称	Anti-APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI5C5 (formerly 5C5), HRP conjugated
反应性	Human, Mouse, Rat
纯化方法	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
同种型	IgG1
缓冲区	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
检测范围	87.0 kDa
灵敏度	Human, Mouse, Rat
免疫原	Full length human recombinant protein of human APP (NP_000475) produced in HEK293T cell.
应用范围	IHC, WB
宿主	Mouse
克隆性	Monoclonal
物种	Mouse
储存条件	Store at -20°C as received.

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.