| 中文名称 |
APC Anti-Human CD101 Antibody[BB27] |
| 中文别名 |
PE Anti-Human CD44 Antibody[P2A1] |
| 英文名称 |
APC Anti-Human CD101 Antibody[BB27] |
| 英文别名 |
P126, V7 |
| 反应性 |
Human |
| 克隆编号 |
BB27 |
| Swissprot |
Q93033 |
| 共轭 |
APC |
| 存储缓冲区 |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| 同种型 |
Mouse IgG1, κ |
| 细胞定位 |
Membrane |
| 同型对照 |
APC Mouse IgG1, κ Isotype Control[MOPC-21] |
| 应用范围 |
FCM |
| 宿主 |
Mouse |
| 克隆性 |
Monoclonal |
| 形态 |
Liquid |
| 储存条件 |
This product can be stored at 2-8°C for 12 months. Do not freeze. |
| 有效期 |
12个月 |
CD101 is a type I transmembrane glycoprotein, known as V7, and P126. It is a 120 kD homodimer, the member of EWI family within Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, a subpopulation of peripheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs posses higher inhibitory function. The biological function of CD101 is still not clear. But it has been found that BB27 antibody is able to inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation of CD101 on dendritic cells is able to induce IL-10 production.
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