| 中文名称 |
APC Anti-Human CD107a/LAMP-1 Antibody[H4A3] |
| 中文别名 |
PE/Cyanine5.5 Anti-Mouse MHC I (H-2Kd) Antibody[SF1.1.10] |
| 英文名称 |
APC Anti-Human CD107a/LAMP-1 Antibody[H4A3] |
| 英文别名 |
CD122, IL-2RB, IL-2Rβ, Interleukin-2 receptor subunit beta, p75 |
| 反应性 |
Human |
| 克隆编号 |
H4A3 |
| Swissprot |
P11279 |
| 共轭 |
APC |
| 存储缓冲区 |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| 同种型 |
Mouse IgG1, κ |
| 细胞定位 |
Membrane |
| 同型对照 |
APC Mouse IgG1, κ Isotype Control[MOPC-21] |
| 应用范围 |
FCM |
| 宿主 |
Mouse |
| 克隆性 |
Monoclonal |
| 形态 |
Liquid |
| 储存条件 |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| 有效期 |
12个月 |
CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
经理
业务员小张
业务员小谭
业务员小罗
微信公众号
