| 中文名称 |
(KO Validated) Vimentin Polyclonal Antibody |
| 英文名称 |
(KO Validated) Vimentin Polyclonal Antibody |
| 英文别名 |
CTRCT30, HEL113, VIM, Vimentin, vimentin |
| 反应性 |
Human;Mouse;Rat |
| 应用性 |
WB;IHC;IF |
| 经过验证的样品 |
Verified Samples in WB: Jurkat, 293T, HeLa, Mouse lung, Mouse testis, Rat lungVerified Samples in IHC: Human tonsil, Human stomachVerified Samples in IF: L929 |
| 纯化方法 |
Affinity purification |
| 共轭 |
Unconjugated |
| 计算分子量 |
53 kDa |
| 观察到的分子量 |
57 kDa |
| 细胞定位 |
Cytoplasm |
| 缓冲区 |
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3. |
| 免疫原 |
Recombinant fusion protein of human Vimentin (NP_003371.2). |
| 应用范围 |
Cancer, Developmental biology, Neuroscience, Signaling transduction, Stem cells |
| 宿主 |
Rabbit |
| 克隆性 |
Polyclonal |
| 储存条件 |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
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