中文名称 |
Anti-PTPRE (PTP epsilon) mouse monoclonal antibody, clone OTI5F2 (formerly 5F2), HRP conjugated |
英文名称 |
Anti-PTPRE (PTP epsilon) mouse monoclonal antibody, clone OTI5F2 (formerly 5F2), HRP conjugated |
反应性 |
Human, Mouse, Rat |
纯化方法 |
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
同种型 |
IgG1 |
缓冲区 |
PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
检测范围 |
80.6 kDa |
灵敏度 |
Human, Mouse, Rat |
免疫原 |
Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell. |
应用范围 |
IF, IHC, WB |
宿主 |
Mouse |
克隆性 |
Monoclonal |
物种 |
Mouse |
储存条件 |
Store at -20°C as received. |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported,one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region,and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.